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For type 2 diabetes, tirzepatide starts at 2.5 mg subcutaneously once weekly for four weeks, then increases by 2.5 mg increments every four weeks as tolerated, per the Mounjaro prescribing information

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Anal Biochem 25:192205 Shabala S, Demidchik V, Shabala L, Cuin TA, Smith SJ, Miller AJ, Newman IA (2006) Extracellular Ca2+ ameliorates NaCl-induced K+ loss from Arabidopsis root and leaf cells by controlling plasma membrane K+-permeable channels

doi: 10.1016/j.psyneuen.2012.11.009, 36 FarrO